Pharmacogenomics: marshalling the human genome to individualise drug therapy
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چکیده
منابع مشابه
Pharmacogenomics: marshalling the human genome to individualise drug therapy.
Pharmacogenomics aims to identify the inherited basis for interindividual differences in drug response, and translate this to molecular diagnostics that can be used to individualise drug therapy. This review uses a number of published examples of inherited differences in drug metabolising enzymes, drug transporters, and drug targets (for example, receptors) to illustrate the potential importanc...
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“Pharmacogenetics deals with pharmacological responses and their modification by hereditary influences.” This definition, offered by Werner Kalow in the first book dedicated to pharmacogenetics, highlights the three pillars of this discipline: pharmacology, genetics and human diversity [1]. Pharmacogenetics has evolved greatly over the 50 years since Kalow ́s book was published, and was rechrist...
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ژورنال
عنوان ژورنال: Gut
سال: 2003
ISSN: 0017-5749
DOI: 10.1136/gut.52.suppl_2.ii10